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BRCAness: Finding the Achilles Heel in Ovarian Cancer

Ovarian cancer is the leading cause of death among gynecological cancers. It exhibits great heterogeneity in tumor biology and treatment response. Germline mutations of DNA repair genes BRCA1/2 are the fundamental defects in hereditary ovarian cancer that expresses a distinct phenotype of high respo...

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Detalhes bibliográficos
Main Authors: Rigakos, Georgios, Razis, Evangelia
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399652/
https://ncbi.nlm.nih.gov/pubmed/22673632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2012-0028
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