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BRCAness: Finding the Achilles Heel in Ovarian Cancer

Ovarian cancer is the leading cause of death among gynecological cancers. It exhibits great heterogeneity in tumor biology and treatment response. Germline mutations of DNA repair genes BRCA1/2 are the fundamental defects in hereditary ovarian cancer that expresses a distinct phenotype of high respo...

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Bibliografiske detaljer
Main Authors: Rigakos, Georgios, Razis, Evangelia
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399652/
https://ncbi.nlm.nih.gov/pubmed/22673632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2012-0028
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