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Lipid-mediated unfolding of 3-beta hydroxysteroid dehydrogenase2 is essential for steroidogenic activity

For inner mitochondrial membrane (IMM) proteins that do not undergo N-terminal cleavage, their activity may occur in the absence of a receptor present in the mitochondrial membrane. One such protein is human 3-beta hydroxysteroid dehydrogenase-2 (3βHSD2), the IMM resident protein responsible for cat...

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Detalhes bibliográficos
Main Authors: Rajapaksha, Maheshinie, Thomas, James L., Streeter, Michael, Prasad, Manoj, Whittal, Randy M., Bell, John D., Bose, Himangshu S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399592/
https://ncbi.nlm.nih.gov/pubmed/22106846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2016102
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