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Betalactam antibiotics interfere with eukaryotic DNA-replication by inhibiting DNA polymerase alpha.
Betalactam antibiotics (BLA) are the most widely used antibacterial drugs in practical medicine. Recent experiments suggested that BLA, especially after "aging" in aqueous solutions, have an inhibitory effect on the growth of a variety of cultured human cells by interfering with DNA synthe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1987
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC339958/ https://ncbi.nlm.nih.gov/pubmed/2827125 |
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