Massive CD8 T Cell Response to Primary HIV Infection in the Setting of Severe Clinical Presentation

Acute HIV-1 infection causes a rapid total body depletion of CD4(+) T cells in most individuals and HIV-1-specific CD8(+) T cell expansion in response to viral replication. A numerically high CD8 T cell response may indicate limited T cell repertoire against HIV and rapid progression. We present a d...

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Detalhes bibliográficos
Main Authors: Arnoczy, Gretchen S., Ferrari, Guido, Goonetilleke, Nilu, Corrah, Tumena, Li, Hui, Kuruc, Joann, Schmitz, John L., McGee, Kara, Hicks, Charles, Eron, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Clinical Perspective
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399555/
https://ncbi.nlm.nih.gov/pubmed/22011008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2011.0145
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