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Hul5 ubiquitin ligase: Good riddance to bad proteins
Failure to eliminate abnormal proteins in the cell is associated with numerous aggregation diseases. Misfolded proteins are normally detected by protein quality control and either refolded or eliminated. The ubiquitin-proteasome system is a major pathway that degrades these unwanted proteins. Ubiqui...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399544/ https://ncbi.nlm.nih.gov/pubmed/22561164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19929 |
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