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Nucleic acid delivery: the missing pieces of the puzzle?

The ability of gene or RNA interference (RNAi) delivery to increase or decrease virtually any protein in a cell opens the path for cures to most diseases that afflict humans. However, their high molecular weight, anionic nature, and instability in the presence of enzymes, pose major obstacles to nuc...

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Bibliografiske detaljer
Main Authors: Nguyen, Juliane, Szoka, Francis C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399092/
https://ncbi.nlm.nih.gov/pubmed/22428908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar3000162
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