Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia

We conducted a genome-wide DNA methylation analysis in CD19(+) B-cells from chronic lymphocytic leukemia (CLL) patients and normal control samples using reduced representation bisulfite sequencing (RRBS). The methylation status of 1.8–2.3 million CpGs in the CLL genome was determined; about 45% of t...

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Main Authors: Pei, Lirong, Choi, Jeong-Hyeon, Liu, Jimei, Lee, Eun-Joon, McCarthy, Brian, Wilson, James M., Speir, Ethan, Awan, Farrukh, Tae, Hongseok, Arthur, Gerald, Schnabel, Jennifer L., Taylor, Kristen H., Wang, Xinguo, Xu, Dong, Ding, Han-Fei, Munn, David H., Caldwell, Charles, Shi, Huidong
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398986/
https://ncbi.nlm.nih.gov/pubmed/22534504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.20237
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