Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma

BACKGROUND: Glioma is the most aggressive tumor of the brain and the most efficient treatments are based on radiotherapy. However, tumors are often resistant to radiotherapy due to an enhanced DNA repair activity. Short and stabilized DNA molecules (Dbait) have recently been proposed as an efficient...

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Detalhes bibliográficos
Main Authors: Coquery, Nicolas, Pannetier, Nicolas, Farion, Régine, Herbette, Aurélie, Azurmendi, Leire, Clarencon, Didier, Bauge, Stéphane, Josserand, Véronique, Rome, Claire, Coll, Jean-Luc, Sun, Jian-Sheng, Barbier, Emmanuel L., Dutreix, Marie, Remy, Chantal C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398898/
https://ncbi.nlm.nih.gov/pubmed/22815765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040567
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