VAPC, an Human Endogenous Inhibitor for Hepatitis C Virus (HCV) Infection, Is Intrinsically Unstructured but Forms a “Fuzzy Complex” with HCV NS5B

Nearly 200 million people are infected by hepatitis C virus (HCV) worldwide. For replicating the HCV genome, the membrane-associated machinery needs to be formed by both HCV non-structural proteins (including NS5B) and human host factors such as VAPB. Recently, the 99-residue VAPC, a splicing varian...

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Autori principali: Goyal, Shaveta, Gupta, Garvita, Qin, Haina, Upadya, Megha Haridas, Tan, Yee Joo, Chow, Vincent T. K., Song, Jianxing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398895/
https://ncbi.nlm.nih.gov/pubmed/22815741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040341
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