CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis

Understanding the mechanisms that regulate angiogenesis and translating these into effective therapies are of enormous scientific and clinical interests. In this report, we demonstrate the central role of CDP-diacylglycerol synthetase (CDS) in the regulation of VEGFA signaling and angiogenesis. CDS...

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Bibliografiska uppgifter
Huvudupphovsmän: Pan, Weijun, Pham, Van N., Stratman, Amber N., Castranova, Daniel, Kamei, Makoto, Kidd, Kameha R., Lo, Brigid D., Shaw, Kenna M., Torres-Vazquez, Jesus, Mikelis, Constantinos M., Gutkind, J. Silvio, Davis, George E., Weinstein, Brant M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2012
Ämnen:
Vascular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398756/
https://ncbi.nlm.nih.gov/pubmed/22649102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-408328
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