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Novel Cues Reinstate Cocaine-Seeking Behavior and Induce Fos Protein Expression as Effectively as Conditioned Cues

Cue reinstatement of extinguished cocaine-seeking behavior is a widely used model of cue-elicited craving in abstinent human addicts. This study examined Fos protein expression in response to cocaine cues or to novel cues as a control for activation produced by test novelty. Rats were trained to sel...

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Detalhes bibliográficos
Main Authors: Bastle, Ryan M, Kufahl, Peter R, Turk, Mari N, Weber, Suzanne M, Pentkowski, Nathan S, Thiel, Kenneth J, Neisewander, Janet L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398726/
https://ncbi.nlm.nih.gov/pubmed/22534624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.60
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