Pioglitazone Adjunctive Therapy for Moderate-to-Severe Major Depressive Disorder: Randomized Double-Blind Placebo-Controlled Trial

Thiazolidinediones have shown antidepressant effect in animal studies, as well as in some uncontrolled studies evaluating human subjects with concurrent major depressive disorder (MDD) and metabolic syndrome. Although these drugs are insulin sensitizers, they also have important anti-inflammatory, n...

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Autors principals: Sepanjnia, Khatereh, Modabbernia, Amirhossein, Ashrafi, Mandana, Modabbernia, Mohammad-Jafar, Akhondzadeh, Shahin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398722/
https://ncbi.nlm.nih.gov/pubmed/22549115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.58
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