Behavioral, Pharmacological, and Immunological Abnormalities after Streptococcal Exposure: A Novel Rat Model of Sydenham Chorea and Related Neuropsychiatric Disorders

Group A streptococcal (GAS) infections and autoimmunity are associated with the onset of a spectrum of neuropsychiatric disorders in children, with the prototypical disorder being Sydenham chorea (SC). Our aim was to develop an animal model that resembled the behavioral, pharmacological, and immunol...

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Detalhes bibliográficos
Main Authors: Brimberg, Lior, Benhar, Itai, Mascaro-Blanco, Adita, Alvarez, Kathy, Lotan, Dafna, Winter, Christine, Klein, Julia, Moses, Allon E, Somnier, Finn E, Leckman, James F, Swedo, Susan E, Cunningham, Madeleine W, Joel, Daphna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398718/
https://ncbi.nlm.nih.gov/pubmed/22534626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.56
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