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Facile Synthesis of Mutagen X (MX): 3-Chloro-4-(dichloromethyl)-5-hydroxy-5H-furan-2-one

3-Chloro-4-(dichloromethyl)-5-hydroxy-5H-furan-2-one (Mutagen X, MX) was synthesized in six steps from commercially-available and inexpensive starting materials (27% overall yield). This synthesis enables the preparation of MX analogs and does not require the use of chlorine gas, as do previously re...

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Bibliographische Detailangaben
Hauptverfasser: Velvadapu, Venkata, McDonnell, Mark E., Jaffe, Eileen K., Reitz, Allen B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398704/
https://ncbi.nlm.nih.gov/pubmed/22822274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.04.044
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