In vitro methylation inhibits the promotor activity of a cloned intracisternal A-particle LTR.
We studied the relation between LTR methylation and expression of the family of endogenous retrovirus-like elements related to mouse intracisternal A-particles (IAP). Comparative HpaII/MspI and HhaI restriction analysis of genomic DNA's showed that in cells and tissues with a low level of IAP gene e...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1986
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2423967/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.10.4343 |
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