Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase–Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis([C])([W])

Diaminopelargonic acid aminotransferase (DAPA-AT) and dethiobiotin synthetase (DTBS) catalyze the antepenultimate and the penultimate steps, respectively, of biotin synthesis. Whereas DAPA-AT and DTBS are encoded by distinct genes in bacteria, in biotin-synthesizing eukaryotes (plants and most fungi...

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Autors principals: Cobessi, David, Dumas, Renaud, Pautre, Virginie, Meinguet, Céline, Ferrer, Jean-Luc, Alban, Claude
Format: Artigo
Idioma:Inglês
Publicat: American Society of Plant Biologists 2012
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Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398567/
https://ncbi.nlm.nih.gov/pubmed/22547782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.112.097675
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