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Hypomethylation of dual specificity phosphatase 22 promoter correlates with duration of service in firefighters and is inducible by low-dose benzo[a]pyrene

OBJECTIVE: Firefighters are chronically exposed to smoke and products of incomplete combustion, which frequently contain PAHs. This study examined the possibility of an association between PAH-induced epigenetic alterations and occupational firefighting exposure. METHODS: Promoter methylation was an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ouyang, Bin, Baxter, C. Stuart, Lam, Hung-Ming, Yeramaneni, Samrat, Levin, Linda, Haynes, Erin, Ho, Shuk-mei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398512/
https://ncbi.nlm.nih.gov/pubmed/22796920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JOM.0b013e31825296bc
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