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Critical Analysis of Treatment Trials of Rhesus Macaques Infected with Borrelia burgdorferi Reveals Important Flaws in Experimental Design

A critical analysis of two treatment trials of Chinese rhesus macaques infected with Borrelia burgdorferi indicates that insufficient attention was placed on documenting the blood levels, pharmacokinetics, and pharmacodynamic parameters of the antibiotics used in this host. Consequently, it is impos...

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Detalhes bibliográficos
Main Authors: Wormser, Gary P., Baker, Phillip J., O'Connell, Susan, Pachner, Andrew R., Schwartz, Ira, Shapiro, Eugene D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398392/
https://ncbi.nlm.nih.gov/pubmed/22620495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vbz.2012.1012
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