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Contributions of Human Enzymes in Carcinogen Metabolism

Considerable support exists for roles of metabolism in modulating the carcinogenic properties of chemicals. In particular, many of these compounds are procarcinogens that require activation to electrophilic forms to exert genotoxic effects. We systematically analyzed the existing literature on metab...

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Detalhes bibliográficos
Main Authors: Rendic, Slobodan, Guengerich, F. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398241/
https://ncbi.nlm.nih.gov/pubmed/22531028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300132k
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