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Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir

Patients infected with human immunodeficiency virus type 1 (HIV-1) often display neurological complications in late stage disease and increased viral loads directly correlated with higher concentrations of extracellular HIV-1 viral protein r (Vpr) in the blood serum and cerebrospinal fluid. Addition...

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Detalhes bibliográficos
Main Authors: Ferrucci, Adriano, Nonnemacher, Michael R., Cohen, Éric A., Wigdahl, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398186/
https://ncbi.nlm.nih.gov/pubmed/22691542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2012.06.002
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