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Epigenetic modifications and chromosome conformations of the beta globin locus throughout development

Human embryonic stem cells provide an alternative to using human embryos for studying developmentally regulated gene expression. The co-expression of high levels of embryonic ε and fetal γ globin by the hESC-derived erythroblasts allows the interrogation of ε globin regulation at the transcriptional...

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Autors principals: Chang, Kai-Hsin, Fang, Xiangdong, Wang, Hao, Huang, Andy, Cao, Hua, Yang, Yadong, Bonig, Halvard, Stamatoyannopoulos, John A., Papayannopoulou, Thalia
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398168/
https://ncbi.nlm.nih.gov/pubmed/22374078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-012-9355-x
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