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Systems Biological Approach of Molecular Descriptors Connectivity: Optimal Descriptors for Oral Bioavailability Prediction

BACKGROUND: Poor oral bioavailability is an important parameter accounting for the failure of the drug candidates. Approximately, 50% of developing drugs fail because of unfavorable oral bioavailability. In silico prediction of oral bioavailability (%F) based on physiochemical properties are highly...

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Bibliografiske detaljer
Main Authors: Ahmed, Shiek S. S. J., Ramakrishnan, V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398012/
https://ncbi.nlm.nih.gov/pubmed/22815781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040654
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