Leukocyte Telomere Length in HIV-Infected and HIV-Exposed Uninfected Children: Shorter Telomeres with Uncontrolled HIV Viremia

OBJECTIVES: Nucleoside reverse transcriptase inhibitors (NRTIs) used in HIV antiretroviral therapy can inhibit human telomerase reverse transcriptase. We therefore investigated whether in utero or childhood exposure to NRTIs affects leukocyte telomere length (LTL), a marker of cellular aging. METHOD...

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Autores principales: Côté, Hélène C. F., Soudeyns, Hugo, Thorne, Anona, Alimenti, Ariane, Lamarre, Valérie, Maan, Evelyn J., Sattha, Beheroze, Singer, Joel, Lapointe, Normand, Money, Deborah M., Forbes, John
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397986/
https://ncbi.nlm.nih.gov/pubmed/22815702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039266
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