Dose-response assessment of nephrotoxicity from a twenty-eight-day combined-exposure to melamine and cyanuric acid in F344 rats

The adulteration of pet food with melamine and derivatives, including cyanuric acid, has been implicated in the kidney failure and death of cats and dogs in the USA and other countries. In a previous 7-day dietary study in F344 rats, we established a no-observed-adverse-effect level (NOAEL) for a co...

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Autori principali: da Costa, Gonçalo Gamboa, Jacob, Cristina C., Von Tungeln, Linda S., Hasbrouck, Nicholas R., Olson, Greg R., Hattan, David G., Reimschuessel, Renate, Beland, Frederick A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397917/
https://ncbi.nlm.nih.gov/pubmed/22579976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.04.031
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