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Reduction of All-trans-retinal in Vertebrate Rod Photoreceptors Requires the Combined Action of RDH8 and RDH12

In vertebrate rod cells, retinoid dehydrogenases/reductases (RDHs) are critical for reducing the reactive aldehyde all-trans-retinal that is released by photoactivated rhodopsin, to all-trans-retinol (vitamin A). Previous studies have shown that RDH8 localizes to photoreceptor outer segments and is...

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Bibliografski detalji
Glavni autori: Chen, Chunhe, Thompson, Debra A., Koutalos, Yiannis
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397894/
https://ncbi.nlm.nih.gov/pubmed/22621924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.354514
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