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Methionine Sulfoxide Reductases Preferentially Reduce Unfolded Oxidized Proteins and Protect Cells from Oxidative Protein Unfolding

Reduction of methionine sulfoxide (MetO) residues in proteins is catalyzed by methionine sulfoxide reductases A (MSRA) and B (MSRB), which act in a stereospecific manner. Catalytic properties of these enzymes were previously established mostly using low molecular weight MetO-containing compounds, wh...

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Detalhes bibliográficos
Main Authors: Tarrago, Lionel, Kaya, Alaattin, Weerapana, Eranthie, Marino, Stefano M., Gladyshev, Vadim N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397870/
https://ncbi.nlm.nih.gov/pubmed/22628550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374520
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