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Modified polynucleotides. VII. Impaired integrity of a synthetic DNA containing the antiherpetic agent 5-isopropyl-2'-deoxyuridine.

5-Isopropyl-2'-deoxyuridine (ip5dU) was recently recognized as a clinically useful antiherpetic (HSV-1) agent. An ip5dU-containing polynucleotide, poly (dA-dT, ip5dU) was prepared to study how physical and bio-organic properties of the synthetic DNA model poly (dA-dT) would change upon partial subst...

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Publicat a:Nucleic Acids Res
Autors principals: Sági, J, Szabolcs, A, Szemźó, A, Otvös, L
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1986
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339784/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3703679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.8.3449
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