Correlation of LINE-1 methylation levels in patient-matched buffy coat, serum, buccal cell and bladder tumor tissue DNA samples

BACKGROUND: Evidence suggests that global methylation levels in blood cell DNA may be a biomarker for cancer risk. To date, most studies have used genomic DNA isolated from blood or urine as a surrogate marker of global DNA methylation levels in bladder tumor tissue. METHODS: A subset of 50 bladder...

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Main Authors: van Bemmel, Dana, Lenz, Petra, Liao, Linda M, Baris, Dalsu, Sternberg, Lawrence R., Warner, Andrew, Johnson, Alison, Jones, Michael, Kida, Masatoshi, Schwenn, Molly, Schned, Alan R., Silverman, Debra T., Rothman, Nathaniel, Moore, Lee E.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397796/
https://ncbi.nlm.nih.gov/pubmed/22539607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-1030
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