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Effect of trypsinization and histone H5 addition on DNA twist and topology in reconstituted minichromosomes.

Free DNA in solution exhibits an untwisting of the double helix with increasing temperature. We have shown previously that when DNA is reconstituted with histones to form nucleosome core particles, both the core DNA and the adjacent linker DNA are constrained from thermal untwisting. The origin of t...

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Autors principals: Morse, R H, Cantor, C R
Format: Artigo
Idioma:Inglês
Publicat: 1986
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC339769/
https://ncbi.nlm.nih.gov/pubmed/3703676
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