Bax expression is a candidate prognostic and predictive marker of colorectal cancer

OBJECTIVE: Since the anti-tumor activity of 5-fluorouracil (5-FU) is due to induction of apoptosis, we assessed the value of expression of key apoptotic molecules (Bax, Bcl-2 and p53) in predicting the efficacy of 5-FU therapy for colorectal adenocarcinomas (CRCs). METHODS: Archival tissues of CRCs...

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Detalhes bibliográficos
Main Authors: Katkoori, Venkat R, Suarez-Cuervo, Catalina, Shanmugam, Chandrakumar, Jhala, Nirag C, Callens, Tom, Messiaen, Ludwine, Posey, James, Bumpers, Harvey L, Meleth, Sreelatha, Grizzle, William E, Manne, Upender
Formato: Artigo
Idioma:Inglês
Publicado em: Pioneer Bioscience Publishing Company 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397579/
https://ncbi.nlm.nih.gov/pubmed/22811811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2010.019
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