Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation

Macrophages are central players in immune response, manifesting divergent phenotypes to control inflammation and innate immunity through release of cytokines and other signaling factors. Recently, the focus on metabolism has been reemphasized as critical signaling and regulatory pathways of human pa...

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Autori principali: Bordbar, Aarash, Mo, Monica L, Nakayasu, Ernesto S, Schrimpe-Rutledge, Alexandra C, Kim, Young-Mo, Metz, Thomas O, Jones, Marcus B, Frank, Bryan C, Smith, Richard D, Peterson, Scott N, Hyduke, Daniel R, Adkins, Joshua N, Palsson, Bernhard O
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397418/
https://ncbi.nlm.nih.gov/pubmed/22735334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.21
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