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Anhedonia requires MC4 receptor-mediated synaptic adaptations in nucleus accumbens

Chronic stress is a strong diathesis for depression in humans and is used to generate animal models of depression. It commonly leads to several major symptoms of depression including dysregulated feeding behavior, anhedonia, and behavioral despair. Although hypotheses defining the neural pathophysio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lim, Byung Kook, Huang, Kee Wui, Grueter, Brad A., Rothwell, Patrick E., Malenka, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397405/
https://ncbi.nlm.nih.gov/pubmed/22785313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11160
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