Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease

Activated partial thromboplastin time (aPTT) and prothrombin time (PT) are clinical tests commonly used to screen for coagulation-factor deficiencies. One genome-wide association study (GWAS) has been reported previously for aPTT, but no GWAS has been reported for PT. We conducted a GWAS and meta-an...

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主要な著者: Tang, Weihong, Schwienbacher, Christine, Lopez, Lorna M., Ben-Shlomo, Yoav, Oudot-Mellakh, Tiphaine, Johnson, Andrew D., Samani, Nilesh J., Basu, Saonli, Gögele, Martin, Davies, Gail, Lowe, Gordon D.O., Tregouet, David-Alexandre, Tan, Adrian, Pankow, James S., Tenesa, Albert, Levy, Daniel, Volpato, Claudia B., Rumley, Ann, Gow, Alan J., Minelli, Cosetta, Yarnell, John W.G., Porteous, David J., Starr, John M., Gallacher, John, Boerwinkle, Eric, Visscher, Peter M., Pramstaller, Peter P., Cushman, Mary, Emilsson, Valur, Plump, Andrew S., Matijevic, Nena, Morange, Pierre-Emmanuel, Deary, Ian J., Hicks, Andrew A., Folsom, Aaron R.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2012
主題:
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オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397273/
https://ncbi.nlm.nih.gov/pubmed/22703881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.05.009
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