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DNA Methylation Based Biomarkers in Non-Invasive Cancer Screening

DNA methylation plays a critical role in the regulation of gene expression, differentiation and in the development of cancer and other diseases. Hypermethylation of CpG islands located in the promoter regions of tumor suppressor genes is now firmly established as the most frequent mechanism for gene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shivapurkar, N., Gazdar, A.F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397200/
https://ncbi.nlm.nih.gov/pubmed/20196733
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