Effect of Hydroxyurea Treatment on Renal Function Parameters: Results from the Multi-Center Placebo-Controlled BABY HUG Clinical Trial for Infants with Sickle Cell Anemia

BACKGROUND: Children with sickle cell anemia (SCA) often develop hyposthenuria and renal hyperfiltration at an early age, possibly contributing to the glomerular injury and renal insufficiency commonly seen later in life. The Phase III randomized double-blinded Clinical Trial of Hydroxyurea in Infan...

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Main Authors: Alvarez, Ofelia, Miller, Scott T., Wang, Winfred C., Luo, Zhaoyu, McCarville, M. Beth, Schwartz, George J., Thompson, Bruce, Howard, Thomas, Iyer, Rathi V., Rana, Sohail R., Rogers, Zora R., Sarnaik, Sharada A., Thornburg, Courtney D., Ware, Russell E.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396762/
https://ncbi.nlm.nih.gov/pubmed/22294512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24100
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