Effect of Hydroxyurea Treatment on Renal Function Parameters: Results from the Multi-Center Placebo-Controlled BABY HUG Clinical Trial for Infants with Sickle Cell Anemia

BACKGROUND: Children with sickle cell anemia (SCA) often develop hyposthenuria and renal hyperfiltration at an early age, possibly contributing to the glomerular injury and renal insufficiency commonly seen later in life. The Phase III randomized double-blinded Clinical Trial of Hydroxyurea in Infan...

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Autori principali: Alvarez, Ofelia, Miller, Scott T., Wang, Winfred C., Luo, Zhaoyu, McCarville, M. Beth, Schwartz, George J., Thompson, Bruce, Howard, Thomas, Iyer, Rathi V., Rana, Sohail R., Rogers, Zora R., Sarnaik, Sharada A., Thornburg, Courtney D., Ware, Russell E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396762/
https://ncbi.nlm.nih.gov/pubmed/22294512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24100
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