Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine

In enterocytes of the small intestine, endocytic trafficking of CFTR channels from the brush border membrane (BBM) to the subapical endosomes requires the minus-end motor, myosin VI (Myo6). The subapical localization of Myo6 is dependent on myosin Ia (Myo1a) the major plus-end motor associated with...

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Hauptverfasser: Kravtsov, Dmitri V., Caputo, Christina, Collaco, Anne, Hoekstra, Nadia, Egan, Marie E., Mooseker, Mark S., Ameen, Nadia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396755/
https://ncbi.nlm.nih.gov/pubmed/22510086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2012.01368.x
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