Defining an EPOR- Regulated Transcriptome for Primary Progenitors, including Tnfr-sf13c as a Novel Mediator of EPO- Dependent Erythroblast Formation

Certain concepts concerning EPO/EPOR action modes have been challenged by in vivo studies: Bcl-x levels are elevated in maturing erythroblasts, but not in their progenitors; truncated EPOR alleles that lack a major p85/PI3K recruitment site nonetheless promote polycythemia; and Erk1 disruption unexp...

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Autors principals: Singh, Seema, Dev, Arvind, Verma, Rakesh, Pradeep, Anamika, Sathyanarayana, Pradeep, Green, Jennifer M., Narayanan, Aishwarya, Wojchowski, Don M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396641/
https://ncbi.nlm.nih.gov/pubmed/22808010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038530
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