Hepcidin-25 in Chronic Hemodialysis Patients Is Related to Residual Kidney Function and Not to Treatment with Erythropoiesis Stimulating Agents

Hepcidin-25, the bioactive form of hepcidin, is a key regulator of iron homeostasis as it induces internalization and degradation of ferroportin, a cellular iron exporter on enterocytes, macrophages and hepatocytes. Hepcidin levels are increased in chronic hemodialysis (HD) patients, but as of yet,...

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Main Authors: van der Weerd, Neelke C., Grooteman, Muriel P. C., Bots, Michiel L., van den Dorpel, Marinus A., den Hoedt, Claire H., Mazairac, Albert H. A., Nubé, Menso J., Penne, E. Lars, Gaillard, Carlo A., Wetzels, Jack F. M., Wiegerinck, Erwin T., Swinkels, Dorine W., Blankestijn, Peter J., ter Wee, Piet M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396629/
https://ncbi.nlm.nih.gov/pubmed/22808058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039783
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