Phevalin (aureusimine B)Production by Staphylococcus aureus Biofilm and Impacts on Human Keratinocyte Gene Expression

Staphylococcus aureus biofilms are associated with chronic skin infections and are orders of magnitude more resistant to antimicrobials and host responses. S. aureus contains conserved nonribosomal peptide synthetases that produce the cyclic dipeptides tyrvalin and phevalin (aureusimine A and B, res...

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Main Authors: Secor, Patrick R., Jennings, Laura K., James, Garth A., Kirker, Kelly R., Pulcini, Elinor deLancey, McInnerney, Kate, Gerlach, Robin, Livinghouse, Tom, Hilmer, Jonathan K., Bothner, Brian, Fleckman, Philip, Olerud, John E., Stewart, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396627/
https://ncbi.nlm.nih.gov/pubmed/22808288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040973
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