ATRA Inhibits the Proliferation of DU145 Prostate Cancer Cells through Reducing the Methylation Level of HOXB13 Gene

All-trans retinoic acid (ATRA) has been widely investigated for treatments of many cancers including prostate cancer. HOXB13, silenced in androgen receptor-negative (AR(−)) prostate cancer cells, plays a role in AR(−) prostate cancer cell growth arrest. In this study we intended to elucidate the mec...

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Detalhes bibliográficos
Main Authors: Liu, Zhiwei, Ren, Guoling, Shangguan, Chenyan, Guo, Lijing, Dong, Zhixiong, Li, Yueyang, Zhang, Weina, Zhao, Li, Hou, Pingfu, Zhang, Yu, Wang, Xiuli, Lu, Jun, Huang, Baiqu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396626/
https://ncbi.nlm.nih.gov/pubmed/22808286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040943
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