A theoretical investigation on the sequence selective binding of adriamycin to double-stranded polynucleotides.

Theoretical computations are performed on the structural and energetical factors involved in the sequence selective binding of adriamycin (ADM) to five self-complementary double-stranded hexanucleotides. Among the two regularly alternating hexanucleotides d (TATATA)2 and d (CGCGCG)2, a stronger bind...

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Bibliographic Details
Main Authors: Chen, K S, Gresh, N, Pullman, B
Format: Artigo
Language:Inglês
Published: 1986
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC339656/
https://ncbi.nlm.nih.gov/pubmed/3960721
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