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Rapid hybridization of nucleic acids using isotachophoresis
We use isotachophoresis (ITP) to control and increase the rate of nucleic acid hybridization reactions in free solution. We present a new physical model, validation experiments, and demonstrations of this assay. We studied the coupled physicochemical processes of preconcentration, mixing, and chemic...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396536/ https://ncbi.nlm.nih.gov/pubmed/22733732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205004109 |
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