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Structural evidence of a new catalytic intermediate in the pathway of ATP hydrolysis by F(1)–ATPase from bovine heart mitochondria

The molecular description of the mechanism of F(1)–ATPase is based mainly on high-resolution structures of the enzyme from mitochondria, coupled with direct observations of rotation in bacterial enzymes. During hydrolysis of ATP, the rotor turns counterclockwise (as viewed from the membrane domain o...

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Detalles Bibliográficos
Main Authors: Rees, David M., Montgomery, Martin G., Leslie, Andrew G. W., Walker, John E.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396519/
https://ncbi.nlm.nih.gov/pubmed/22733764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207587109
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