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Multistep molecular mechanism for Bone morphogenetic protein extracellular transport in the Drosophila embryo

In the Drosophila embryo, formation of a bone morphogenetic protein (BMP) morphogen gradient requires transport of a heterodimer of the BMPs Decapentaplegic (Dpp) and Screw (Scw) in a protein shuttling complex. Although the core components of the shuttling complex—Short Gastrulation (Sog) and Twiste...

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Autors principals: Sawala, Annick, Sutcliffe, Catherine, Ashe, Hilary L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396515/
https://ncbi.nlm.nih.gov/pubmed/22733779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202781109
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