The actin regulator N-WASp is required for muscle-cell fusion in mice

A fundamental aspect of skeletal myogenesis involves extensive rounds of cell fusion, in which individual myoblasts are incorporated into growing muscle fibers. Here we demonstrate that N-WASp, a ubiquitous nucleation-promoting factor of branched microfilament arrays, is an essential contributor to...

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Bibliographische Detailangaben
Hauptverfasser: Gruenbaum-Cohen, Yael, Harel, Itamar, Umansky, Kfir-Baruch, Tzahor, Eldad, Snapper, Scott B., Shilo, Ben-Zion, Schejter, Eyal D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396508/
https://ncbi.nlm.nih.gov/pubmed/22736793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116065109
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