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Probing the caveolin-1 P132L mutant: Critical insights into its oligomeric behavior and structure

Caveolin-1 is the most important protein found in caveolae, which are cell surface invaginations of the plasma membrane that act as signaling platforms. A single point mutation in the transmembrane domain of caveolin-1 (proline 132 to leucine) has deleterious effects on caveolae formation in vivo, a...

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Bibliografiske detaljer
Main Authors: Rieth, Monica D., Lee, Jinwoo, Glover, Kerney Jebrell
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396432/
https://ncbi.nlm.nih.gov/pubmed/22506673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3001853
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