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Impact of microRNA regulation on variation in human gene expression

MicroRNAs (miRNAs) are endogenously expressed small RNAs that regulate expression of mRNAs at the post-transcriptional level. The consequence of miRNA regulation is hypothesized to reduce the expression variation of target genes. However, it is possible that mutations in miRNAs and target sites caus...

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Detalhes bibliográficos
Main Authors: Lu, Jian, Clark, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396366/
https://ncbi.nlm.nih.gov/pubmed/22456605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.132514.111
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