Ethyl pyruvate for the treatment of acetaminophen intoxication: alternative to N-acetylcysteine?

N-acetylcysteine is the classical antidote for acetaminophen overdose-induced hepatotoxicity, but its efficacy is limited by the need for early and only temporary treatment. Therefore, Yang and colleagues tested the hypothesis of whether ethyl pyruvate - another anti-inflammatory and antioxidant com...

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Detaylı Bibliyografya
Asıl Yazarlar: Wagner, Florian, Asfar, Pierre, Georgieff, Michael, Radermacher, Peter, Wagner, Katja
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Commentary
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396244/
https://ncbi.nlm.nih.gov/pubmed/22348679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11153
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