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Cellular mechanotransduction: Filamin A strains to regulate motility

A new study from Ehrlicher et al. in Nature finds filamin A strain-dependent increases in integrin and decreases in FilGAP binding using fluorescence loss after photoconversion. This indicates that there may be direct mechanotransduction of filamin A strain into increased matrix-cytoskeleton linkage...

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Detalhes bibliográficos
Main Authors: Lynch, Christopher D., Sheetz, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396208/
https://ncbi.nlm.nih.gov/pubmed/22115457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.10.020
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